Mitotic activity in the human epidermis

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Mitotic activity in the human epidermis.

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Mitotic Diversity in Homeostatic Human Interfollicular Epidermis

Despite decades of skin research, regulation of proliferation and homeostasis in human epidermis is still insufficiently understood. To address the role of mitoses in tissue regulation, we utilized human long-term skin equivalents and systematically assessed mitoses during early epidermal development and long-term epidermal regeneration. We now demonstrate four different orientations: (1) horiz...

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Mitotic Langerhans Cells in the Normal Human Epidermis: Light and Electron Microscopic Observations in All Mitotic Phases

In three experiments of the normal human epidermis under different biopsy and fixative buffer conditions, Langerhans cells (LCs) in all mitotic phases were found with the Thin-Section-Reembedding and Ultrathin-Sectioning (TRUS) technique; two in the prophase, five in the metaphase, two in the anaphase and two in the telophase. The serial light microscopic examination showed many characteristic ...

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Robust control of mitotic spindle orientation in the developing epidermis

Progenitor cells must balance self-amplification and production of differentiated progeny during development and homeostasis. In the epidermis, progenitors divide symmetrically to increase surface area and asymmetrically to promote stratification. In this study, we show that individual epidermal cells can undergo both types of division, and therefore, the balance is provided by the sum of indiv...

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Lactic dehydrogenase activity in human epidermis: semiquantitative histochemical study.

SASAI, Y. Lactic Dehydrogenase Activity in Human Epidermis: Semiquantita tive Histochemical Study. Tohoku J. exp. Med ., 1972, 108 (4), 327-336 The graphical method of Lineweaver-Burk to the histoehemical system was applied to obtain quantitative information on the lactic dehydrogenase activity in human epidermis. In vitro experiment showed that the incubation time necessary for yielding a cert...

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ژورنال

عنوان ژورنال: The Anatomical Record

سال: 1959

ISSN: 0003-276X,1097-0185

DOI: 10.1002/ar.1091350103